5-Amino-1-(2-Hydroxyethyl)pyrazole CAS 73616-27-0 Purity >99.0% (HPLC) Cefoselis Intermediate

Short Description:

Name: 5-Amino-1-(2-Hydroxyethyl)pyrazole

CAS: 73616-27-0

Purity: >99.0% (HPLC)

Appearance: Light Yellow to Reddish Yellow Powder

High Quality, Commercial Production

Intermediates of Cefoselis & Cefoselis Sulfate

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Product Detail

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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of 5-Amino-1-(2-Hydroxyethyl)pyrazole (CAS: 73616-27-0) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	5-Amino-1-(2-Hydroxyethyl)pyrazole
Synonyms	3-Aminopyrazole-2-Ethanol; 3-Amino-2-Pyrazoleethanol; 5-Amino-1-(beta-Hydroxyethyl)pyrazole
CAS Number	73616-27-0
CAT Number	RF2586
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C5H9N3O
Molecular Weight	127.15
Melting Point	107.0 to 109.0℃
Boiling Point	140℃/0.04 mmHg
Density	1.35±0.10 g/cm3
Sensitive	Air Sensitive, Heat Sensitive
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Light Yellow to Reddish Yellow Powder
Purity / Analysis Method	>99.0% (HPLC)
Purity / Analysis Method	>98.0% (Nonaqueous Titration)
Melting Point	107.0 to 109.0℃
Loss on Drying	<0.50%
Total Impurities	<1.00%
1 H NMR Spectrum	Consistent With Structure
Usage	Intermediates of Cefoselis (CAS: 122841-10-5) & Cefoselis Sulfate (CAS: 122841-12-7)

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

5-Amino-1-(2-Hydroxyethyl)pyrazole (CAS: 73616-27-0) is an intermediates of Cefoselis (CAS: 122841-10-5) & Cefoselis Sulfate (CAS: 122841-12-7). Cefoselis is a new fourth-generation cephalosporin and was launched in Japan as a parenteral antibiotic for a variety of infections including Staphylococcus aureus (particularly the methicillin-resistant MRSA) and Pseudornonas aeruginosa. It can be prepared in 3 related ways, all using 2- pyrazolomethyl-3-cephem-4-carboxylic as the key intermediate. In preclinical studies, Cefolesis had better MIC50s than Ceftazidime against Streptococcus pneurnoniae or Staphflococcus aureus (methicillin-sensitive MSSA or resistant MRSA) and showed significant antibacterial activity against Citrobacter and Enterobacter. Cefolesis is well tolerated in clinical studies, being eliminated mainly via glomerular filtration in humans.